WEAKENING OF TROPICAL SEA BREEZE CONVECTIVE SYSTEMS THROUGH INTERACTIONS OF AEROSOL, RADIATION, AND SOIL MOISTURE

Weakening of tropical sea breeze convective systems through interactions of aerosol, radiation, and soil moisture

This study investigates how the enhanced loading of microphysically and radiatively active aerosol particles impacts tropical sea breeze convective systems and whether these impacts are modulated by the many environments that support these cloud systems.Comparisons of two 130-member pristine and polluted ensembles demonstrate that aerosol direct ef

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Metabolic Reprogramming via ACOD1 depletion enhances function of human induced pluripotent stem cell-derived CAR-macrophages in solid tumors

Abstract The pro-inflammatory state of macrophages, underpinned by their metabolic condition, is essentially affecting their capacity of combating tumor cells.Here we find, via a pooled metabolic gene knockout CRISPR screen that KEAP1 and ACOD1 are strong regulators of the pro-inflammatory state in macrophages.We show that ACOD1 knockout macrophage

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